Chemical approaches to brain function, Vol. 5
نویسندگان
چکیده
منابع مشابه
Progress in Chemical Toxicology, Vol. 5
461 base used for the original analysis is predominantly that seen in normal patients, while the critical interpretation is the sick patient. This reviewer, for example, recently saw a liver with extensive metastases proven to be over 4700 g at necropsy (3 times normal weight) measured as normal approximately 2 weeks before death by the author's techniques in the author's nuclear facility. It w...
متن کاملChemical approaches to understanding O-GlcNAc glycosylation in the brain.
O-GlcNAc glycosylation is a unique, dynamic form of glycosylation found on intracellular proteins of all multicellular organisms. Studies suggest that O-GlcNAc represents a key regulatory modification in the brain, contributing to transcriptional regulation, neuronal communication and neurodegenerative disease. Recently, several new chemical tools have been developed to detect and study the mod...
متن کاملAn overview of therapeutic approaches to brain tumor stem cells
Primary and secondary malignant central nervous system (CNS) tumors are devastating invasive tumors able to give rise to many kinds of differentiated tumor cells. Glioblastoma multiform (GBM), is the most malignant brain tumor, in which its growth and persistence depend on cancer stem cells with enhanced DNA damage repair program that also induces recurrence and resists current chemo- and radi...
متن کاملChemical approaches to mapping the function of post-translational modifications.
Strategies for the chemical construction of synthetic proteins with precisely positioned post-translational modifications or their mimics offer a powerful method for dissecting the complexity of functional protein alteration and the associated complexity of proteomes.
متن کاملChemical approaches to glycobiology.
Glycans are ubiquitous components of all organisms. Efforts to elucidate glycan function and to understand how they are assembled and disassembled can reap benefits in fields ranging from bioenergy to human medicine. Significant advances in our knowledge of glycan biosynthesis and function are emerging, and chemical biology approaches are accelerating the pace of discovery. Novel strategies for...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Electroencephalography and Clinical Neurophysiology
سال: 1974
ISSN: 0013-4694
DOI: 10.1016/0013-4694(74)90126-6